A Prescription for Adolescent Depression (Warning: May Cause Hostility, Insomnia and Akathisia)
In 1993, a proposal was developed to study the drug for use in adolescent “depression”, and Study 329 was launched. Study 329 did not show a clear benefit compared to placebo, and some study participants suffered serious side effects. The researchers played these down by coding suicidality as lability, and overlooking certain adverse events altogether.