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In 1993, a proposal was developed to study the drug for use in adolescent “depression”, and Study 329 was launched. Study 329 did not show a clear benefit compared to placebo, and some study participants suffered serious side effects. The researchers played these down by coding suicidality as lability, and overlooking certain adverse events altogether.
A Review by Leemon B. McHenry, California State University Children of the Cure: Missing Data, Lost Lives and Antidepressants By David Healy, Joanna Le Noury and Julie Wood Samizdat Health, 2020, ix +269 pp. Subjecting children to antidepressant drugs that did not outperform sugar pills and that increased suicidality would seem to have been an […]
Children of the Cure offers either a fairy tale or an epic take (pay your money and make your own call) on Study 329 – the most famous clinical trial in medicine. There are other takes on what happened in the pipeline from the more academic Illusions of Evidence-Based Medicine by Jureidini and McHenry to Paul Scott’s The Malcharist, which may be satire or may be all too real, difficult to tell, and a compelling screenplay. These books complement Jim Gottstein’s The Zyprexa Papers.
“During my research, I found hundreds of cases of Seroxat-induced “suicide.” I then came across a notorious study that GSK had carried out in the late 90s, a study they termed “329.” The study’s outcome had been posted in a journal online, and all seemed to be well and good. It appeared that Seroxat showed remarkable efficacy in children and adolescents. Why then were children and adolescents dying violent deaths whilst taking it, I wondered?
~ Bob Fiddaman, activist and blogger on drug-related injuries
The story is depressing and tragic, one of many similar tales that have appeared in the past two decades. Clinicians have the skills to assess new treatments, but their independence and financial support must be assured by independent non-industry sources. Children of the Cure is a frightening and tragic story that warrants governmental and public attention. A book review by Max Fink, M.D., Professor of Psychiatry and Neurology Emeritus
StonyBrook University College of Medicine
When Samizdat published Children of the Cure on Amazon, there was discomfort in some quarters. The discomfort was practical for some. Mark Carter from Auckland told us it would take 154 NZ dollars to buy two copies and have then posted to him – he had to go through Amazon.com as Amazon.com.au for some strange reason does […]
The Decapitation of Care is a short text that takes issue with the current hegemonic thought that has elevated health technology to a position of being the new route to salvation. The starting point is that the thoughtless employment of this technology is harming people — it has started to shorten their life expectancy and has undermined healthcare and the doctor-patient relationship. David Healy, therefore, invites us to “stop doing” in a protocolized and standardized way, and stop to think.
by John Dan Stone, Age of Autism, UK Editor A welcome for David Healy’s new, short polemical volume The Decapitation of Care. Healy as ever likes to express himself in terms of historical theatre — the comparison with oppressive political situations of past as well as the roots of this present oppressive situation in the […]
By Pamela Stavropoulos Author: Living under Liberalism Significantly, psychiatrist and cultural critic David Healy characterises his most recent publication, A Short History of the Rise and Fall of Healthcare as ‘the Health care Manifesto’. Defined as ‘a written statement declaring publicly the intentions, motives, or views of its issuer’ a manifesto is generally both a […]
