Prozac, arguably the most famous drug of our lifetimes, was never approved for sale.
by Paul John Scott
Rather, Prozac when combined with anti-anxiety medication was approved for sale. In an unpromising design that seems so very much at home with the rest of the strange deeds set forth in this clarifying, well-curated new book, for a third-to-half of the patients studied, the antidepressant fluoxetine was studied as part of a cocktail, even though the approval went to Prozac alone.
This was because, when taken by itself, Prozac made people too agitated.