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Malcharist: Fact or Fiction? Big Pharma, Psychiatry and Ghostwriters

Malcharist, by Paul John Scott, is a fictional account of one of psychiatry’s most influential key opinion leaders (KOLs), his ghostwriter, and a journalist on the trail of a big scandal in the world of Big Pharma. The story didn’t happen in reality, but Scott has done his homework in such a way that one of medicine’s darkest secrets is exposed in all of its sordid detail.

For those of us familiar with industry-sponsored clinical trials such as GlaxoSmithKline’s studies 329 and 352, it doesn’t take much imagination to draw analogies to an all-too-common theme: a psychiatrist and a ghostwriter who helped create an illusion. He takes all the credit for her labors and she disappears into the background. What is presented to the medical community, however, is a story of pharmaceutical marketing masquerading as science.

Filed Under: Books, Malcharist, Reviews

CounterPunch on The Zyprexa Papers

CounterPunch.org has just published a great review of The Zyprexa Papers, Jim Gottstein’s book about his battle over Zyprexa (Olanzapine) with drug marketing giant Eli Lilly. Written by Bruce E. Levine, a psychologist and social critic, the review addresses the broad social issues raised by Jim Gottstein’s story. “The Zyprexa Papers is not simply about the harm done by blockbuster psychiatric drugs and drug company illegal marketing. It is also about the perversion of the U.S. legal system, as Gottstein illuminates the courts’ use of secrecy orders in settlement agreements to the detriment of the public.”

Filed Under: News, Reviews

Malcharist Reviews: A truly spellbinding thriller

Malcharist Reviews on Amazon. “Don’t Miss This Brilliant and Breathtaking First Novel by The Gifted Paul John Scott,”Dr. T. “The Truth Is Stranger Than Fiction,” Kevin Miller. “Fascinating and fun. Worth the time and money,” Jeff

Filed Under: Books, Malcharist, Reviews

The lessons of Study 329: How fraud in psychiatric drug research got normalised

Study 329, which was a trial of paroxetine for depression in adolescents, is often held up as the poster child for fraud in clinical trials of psychiatric drugs. In Children of the cure: Missing data, lost lives and antidepressants, David Healy, Joanna Le Noury and Julie Wood painstakingly detail the entire sordid affair, including efforts to get the study retracted and to reanalyse the patient-level data. However, they do so with a larger purpose in mind. Study 329 is not presented as an aberration, but rather as emblematic of a systemic failure in modern medicine (or at least in psychiatry), which leads to prescribing practices that do great harm.

Filed Under: Books, Children of the Cure, Study329

A rollicking good read that gives Pharma a run for its money

Malcharist Review by Annie Bevan Malcharist bounds like a hound as Lee Majors spies with his own eyes, his master is unaware he is up-the-creek, without a paddle. Griffin Wagner is fighting the devil’s work and suddenly his botched-up visions give him a break into a new world where right is wrong and wrong is […]

Filed Under: Books, Malcharist, Reviews

A Ghost Story: Children of the Cure

I suspect the title of this book by David Healy, Joanna Le Noury, and Julie Wood, was inspired by the Stephen King horror story Children of the Corn.  In the Stephen King story, it is the children who are evil.  In Dr. Healy’s book, it is the adults who are perpetrating evil by exaggerating benefits and minimizing harm of antidepressant use in children. A Review of Children of the Cure by David Antonuccio, Ph.D.

Filed Under: Children of the Cure, Reviews, Study329

This Novel Will Swallow You Whole

This is a novel that takes the reader deep inside the Pharmaceutical Empire which invents diseases, creates “patient advocacy organizations” to sell these diseases to the public, manufactures and controls the evidence base purporting to show their nostrums are safe and effective remedies for these diseases, relentlessly gaslights those unfortunate victims harmed by their patent medicines, and smears all who question any of this as “Luddites, anti-vaxxers, tin-foil hatters, and Scientologists.”

Filed Under: Books, Malcharist, Reviews

The Hemingway Effect – Malcharist

This week, Samizdat announces our long-awaited release of Malcharist, an accessible and unusually realistic contemporary fiction work by Paul John Scott. The book is a page-turner about the corruption of clinical trials told through a medical ghostwriter’s crisis of conscience. Set in Manhattan in 2010 and laced with dark humor throughout its fast 352 pages, it […]

Filed Under: Books, Malcharist, Reviews

Malcharist

A novel by Paul John Scott

A closely-observed, panoramic thriller about medical science gone wrong, and the people who make dangerous pills seem safe.

It’s Manhattan in the winter of 2010, and Shivani Patel is carrying the secrets of a trade that no one understands: medical ghostwriting. A Cambridge-trained scientist and wordsmith for the world’s largest drugmaker, she makes her soaring pay by delivering the sleight-of-hand needed to move new drugs into journals and onto market. Then she watches as a parade of aging males take credit for her work…

Filed Under: Books, Malcharist

A Cure for Fraudulent Reporting

Children of the Cure is first a deep dive into the fraudulent reporting of “Study 329,” the clinical trial of Paxil (paroxetine) that launched an epidemic of drug-induced suicides by children and adolescents in the United States and many other countries.  It is an indictment of Paxil’s manufacturer, Glaxo Smith Kline (GSK) and the many doctors who were paid to have their names appear on a study that was ghost-written by GSK.  A review by Jim Gottstein, author of The Zyprexa Papers

Filed Under: Books, Children of the Cure, Reviews, Study329

“Paxil turned me into a monster”

“I tried killing myself thirty times.” So says Vickie, a nurse from Philadelphia who was first prescribed Paxil at the age of ten for something called “social anxiety disorder.” For the past several years, I have borne witness to people like Vickie – wonderful, creative, caring people – who were turned into burned-out shells of their former selves after getting hooked on antidepressants and other psychiatric drugs. Most of these people began taking these drugs for the most banal reasons you could imagine… By Patrick D Hahn @Patrickhahn

Filed Under: Books, Children of the Cure, Reviews, Study329

Children of the Cure Sends Shock Waves

Children of the Cure should send shock waves throughout a pharmaceutical industry hell-bent on promoting drugs at any cost and waken up those whose main interests lie in the safeguarding of the general public.

Never before has a book been unleashed on the market which unmasks the lengths a British pharmaceutical company will go to ensure that young children are caught up in the unsavoury shenanigans of ghosting and distorting clinical trial data just to increase sales of a drug called Paroxetine.

A Riff and Review by Annie Bevan

Filed Under: Children of the Cure, Reviews, Study329

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